Harnessing Yeast Peroxisomes for Biosynthesis of Fatty-Acid-Derived Biofuels and Chemicals with Relieved Side-Pathway Competition

Zhou, Y.J. , Buijs, N.A.e, Zhu, Z., Gómez, D.O., Boonsombuti, A., Siewers, V., Nielsen, J.   Abstract   Establishing efficient synthetic pathways for microbial production of biochemicals is often hampered by competing pathways and/or insufficient precursor supply. Compartmentalization in cellular organelles can isolate synthetic pathways from competing pathways, and provide a compact and suitable environment…